Glutamiinisyntetaasi
Aliases for GLUL Gene
- GeneCards Symbol: GLUL 2
- Glutamate-Ammonia Ligase 2 3 5
- Glutamine Synthetase 2 3 4
- GLNS 3 4 5
- Palmitoyltransferase GLUL 3 4
- EC 6.3.1.2 4 47
- GS 3 4
- Glutamate-Ammonia Ligase (Glutamine Synthase) 2
- Cell Proliferation-Inducing Protein 59 3
- Proliferation-Inducing Protein 43 3
- Glutamate--Ammonia Ligase 4
- Glutamate Decarboxylase 3
- Glutamine Synthase 3
- EC 2.3.1.225 4
- DEE116 3
- PIG43 3
- PIG59 3
| Glutamine Deficiency, Congenital 1 4 6 107 136 |
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2 publication(s)
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| Developmental And Epileptic Encephalopathy 116 1 6 107 136 |
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1 publication(s)
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| Congenital Brain Dysgenesis Due To Glutamine Synthetase Deficiency 97 99 107 |
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2 publication(s)
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| Developmental And Epileptic Encephalopathy 16 107 |
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1 publication(s)
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| Hepatocellular Carcinoma 1 21 63 135 |
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Hepatocellular Carcinoma (HCC)
MCID: HPT023
Info Score: 93
Summary
(AI-Supported)
Hepatocellular carcinoma is a primary liver cancer derived from well-differentiated hepatocytes. It is the most common type of primary liver cancer in adults and is the third leading cause of cancer-related deaths worldwide. Major risk factors include chronic hepatitis B and C infections, dietary aflatoxin exposure, alcoholic cirrhosis, and cirrhosis due to other causes. Symptoms include hepatic mass, abdominal pain, jaundice, cachexia, and liver failure. Treatment options include surgery, radiation, chemotherapy, and liver transplantation. Hepatoblastomas, a rare form of liver cancer, are thought to be derived from undifferentiated hepatocytes and most commonly occur in children under 3 years of age.
Categories
- 1,210 genes associated with Hepatocellular Carcinoma
- 98 with high evidence (Elite gene associations)
- 1,112 non-elite and text-mined gene associations
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