RNF223 , Ring finger protein 223. Ip36.33 omaa assosiaatiota myasteniaan.

 Minkälainen STRING  ympäristö tällä  geenillä ja proteiinilla on.

 https://www.genecards.org/cgi-bin/carddisp.pl?gene=RNF223&keywords=RNF223

 UBC on lähellä RNF223:a muta yhdysviivaa niitten kesken ei  vedetä string kartassa.   UBC  keskipisteestä katsottuna on paljon  kartoitettuja  proteiineja. 

Lähellä on GABARAP moduli. 

Gamma-aminobutyric acid receptor-associated protein; Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, paticipates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with ly [...]

Identifier: ENSP00000306866, GABARAP
Organism: Homo sapiens 

 

GABARAP1

 Information
Gamma-aminobutyric acid receptor-associated protein-like 1; GABA type A receptor associated protein like 1.

Identifier: ENSP00000411256, GABARAPL1
Organism: Homo sapiens 

 

GABARAP like 2

 Information
Gamma-aminobutyric acid receptor-associated protein-like 2; Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved [...]

Identifier: ENSP00000037243, GABARAPL2